Sunday, October 24, 2010

Stem Cells and Regenerative Biology


Major Topics for Discussion:
1)      What are Stem Cells?
2)      What are the major types of Stem Cells and where are they found?
3)      Advantages & Disadvantages to ESCs and ASCs
4)      Why are Stem Cells so very important?
5)      The Controversy over Stem Cells?

What are Stem Cells?
Stem Cells are extraordinary because:
            They can divide and make identical copies of
    themselves over and over again (Self-Renewal)
             Remain Unspecialized with no ‘specific’ 
    function  or become . . . .
             Specialized (Differentiated) w/ the potential
    to produce over 200 different types of cells in 
    the body


The Major Types of Stem Cells
  1. Embryonic Stem Cells
          From blastocysts left over from In-Vitro Fertilization in the laboratory
          From aborted fetuses
B. Adult Stem Cells
          Stem cells have been found in the blood, bone marrow, liver, kidney, cornea, dental pulp, umbilical cord, brain, skin, muscle, salivary gland . . . . 


Why is Stem Cell Research So Important to All of Us?
ü  Stem cells allow us to study how organisms grow and develop over time.
ü  Stem cells can replace diseased or damaged cells that can not heal or renew themselves.
ü  We can test different substances (drugs and chemicals) on stem cells.
ü  We can get a better understanding of our “genetic machinery.”

What Human Diseases are Currently Being Treated with Stem Cells?
          Parkinson’s Disease
          Leukemia (Bone Marrow Transplants)
          Skin Grafts resulting from severe burns
Stem Cell Therapy has the Potential to:
          Regenerate tissues/organs
Cure diseases like diabetes, multiple sclerosis, etc

Why the Controversy Over Stem cells?
          Embryonic Stem cells are derived from extra blastocysts that would otherwise be discarded following IVF.
          Extracting stem cells destroys the developing blastocyst (embryo).
-Questions for Consideration-
Is an embryo a person?
Is it morally acceptable to use embryos for research?
When do we become “human beings?”

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