Sunday, October 24, 2010

Stem Cells and Regenerative Biology


Major Topics for Discussion:
1)      What are Stem Cells?
2)      What are the major types of Stem Cells and where are they found?
3)      Advantages & Disadvantages to ESCs and ASCs
4)      Why are Stem Cells so very important?
5)      The Controversy over Stem Cells?

What are Stem Cells?
Stem Cells are extraordinary because:
•            They can divide and make identical copies of
    themselves over and over again (Self-Renewal)
•             Remain Unspecialized with no ‘specific’ 
    function  or become . . . .
•             Specialized (Differentiated) w/ the potential
    to produce over 200 different types of cells in 
    the body


The Major Types of Stem Cells
  1. Embryonic Stem Cells
•          From blastocysts left over from In-Vitro Fertilization in the laboratory
•          From aborted fetuses
B. Adult Stem Cells
•          Stem cells have been found in the blood, bone marrow, liver, kidney, cornea, dental pulp, umbilical cord, brain, skin, muscle, salivary gland . . . . 


Why is Stem Cell Research So Important to All of Us?
ü  Stem cells allow us to study how organisms grow and develop over time.
ü  Stem cells can replace diseased or damaged cells that can not heal or renew themselves.
ü  We can test different substances (drugs and chemicals) on stem cells.
ü  We can get a better understanding of our “genetic machinery.”

What Human Diseases are Currently Being Treated with Stem Cells?
•          Parkinson’s Disease
•          Leukemia (Bone Marrow Transplants)
•          Skin Grafts resulting from severe burns
Stem Cell Therapy has the Potential to:
•          Regenerate tissues/organs
Cure diseases like diabetes, multiple sclerosis, etc

Why the Controversy Over Stem cells?
•          Embryonic Stem cells are derived from extra blastocysts that would otherwise be discarded following IVF.
•          Extracting stem cells destroys the developing blastocyst (embryo).
-Questions for Consideration-
Is an embryo a person?
Is it morally acceptable to use embryos for research?
When do we become “human beings?”

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